In the first episode "The Pilot" Chandler is the first person to speak when he is talking about his dream. In the last episode "The Last One" Chandler is the last person to speak after they say to get coffee, and he asks where.
While it is right that in the TV version of the first episode (Pilot 1.1) Chandler started the show with his dream-talk (his dream was a gr8 one , remember?) , in the uncut version , it is was Monica who started talking (There's nothing to tell!) , its an ironic start to a show where you have everything to tell, doesn't it ?
Heres the conversation of that :
SCENE 1: CENTRAL PERK. (ALL PRESENT EXCEPT RACHEL AND ROSS)
MONICA: There's nothing to tell! He's just some guy I work with!
JOEY: C'mon, you're going out with the guy! There's gotta be something wrong with him!
CHANDLER: So does he have a hump? A hump and a hairpiece?
PHOEBE: Wait, does he eat chalk?
(THE OTHERS STARE, BEMUSED)
PHOEBE: Just, 'cause, I don't want her to go through what I went through with Carl- oh!
MONICA: Okay, everybody relax. This is not even a date. It's just two people going out to dinner and- not having sex.
CHANDLER: Sounds like a date to me.